New Series of Potent, Orally Bioavailable, Non-Peptidic Cyclic Sulfones as HIV-1 Protease Inhibitors

Abstract

ADVERTISEMENT RETURN TO ISSUELetterNEXTNew Series of Potent, Orally Bioavailable, Non-Peptidic Cyclic Sulfones as HIV-1 Protease InhibitorsChoung U. Kim, Lawrence R. McGee, Steven H. Krawczyk, Erik Harwood, Yoko Harada, S. Swaminathan, Norbert Bischofberger, Ming S. Chen, Julie M. Cherrington, Shelly F. Xiong, Linda Griffin, Kenneth C. Cundy, Angela Lee, Betty Yu, Sergli Gulnik, and John W. EricksonView Author Information Gilead Sciences Inc., 353 Lakeside Drive, Foster City, California 94404, and Structural Biochemistry Program, SAIC Frederick, NCI-Frederick Cancer, Research and Development Center, Frederick, Maryland 21702Cite this: J. Med. Chem. 1996, 39, 18, 3431–3434Publication Date (Web):August 30, 1996Publication History Received7 May 1996Published online30 August 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jm960340ohttps://doi.org/10.1021/jm960340orapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views574Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Antimicrobial agents,Inhibitors,Molecular structure,Peptides and proteins,Viruses Get e-Alerts