Resistance to metronidazole, clarithromycin and levofloxacin of <i>Helicobacter pylori</i> before and after clarithromycin‐based therapy in Taiwan

Abstract

The levofloxacin resistance of naive H. pylori remains less than 10% in Taiwan. With relatively lower resistance to levofloxacin than to metronidazole of the H. pylori isolates collected after a failed clarithromycin-based therapy, proton pump inhibitor-levofloxacin-amoxicillin may be an alternative choice to serve as the second-line therapy.