Rhodium-Catalyzed Oxidative <i>ortho</i>-Acylation of Benzamides with Aldehydes: Direct Functionalization of the sp² C–H Bond

Abstract

A rhodium-catalyzed oxidative acylation of benzamides with aryl aldehydes via direct sp(2) C-H bond cleavage is described. In the presence of [Cp*RhCl(2)](2), AgSbF(6), and silver carbonate as an oxidant, N,N-diethyl benzamides can be effectively carbonylated to yield ortho-acyl benzamides.