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Molecular cloning and mapping of a human cDNA (SC5DL) encoding a protein homologous to fungal sterol-C5-desaturase

DOI

29

Citations

0

References

1996

Year

M. Matsushima, Johji Inazawa, E. Takahashi, Kaoru Suzumori, Yoshimasa Nakamura
Cytogenetic and Genome Research

Abstract

We have isolated a human cDNA clone homologous to fungal ERG3, a gene encoding sterol C-5 desaturase. The full nucleotide sequence of this human cDNA revealed a 708-bp open reading frame that encodes a 236-amino-acid polypeptide. The gene was expressed in all normal human tissues examined. We determined its location to chromosome 11q23.3 by fluorescence in situ hybridization.