Elevated levels of miR-146a and miR-155 in kidney biopsy and urine from patients with IgA nephropathy.

Abstract

We conclude that intra-renal and urinary levels of miR-146a and miR-155 were significantly elevated in IgAN, and the degree of upregulation correlates with clinical and histological severity of the disease. Our results suggested miR-146a and miR-155 might play an important role in the pathophysiology of IgAN.