PERITUBULAR CAPILLARY BASEMENT MEMBRANE REDUPLICATION IN ALLOGRAFTS AND NATIVE KIDNEY DISEASE

Abstract

We conclude that in transplants, there is a strong association between well-developed PTCR and TG, while the significance of mild PTCR and its predictive value in the absence of TG is unclear. PTCR also occurs in certain native kidney diseases, though the association is not as strong as that for TG. We suggest that repeated endothelial injury, including immunologic injury, may be the cause of this lesion both in allografts and native kidneys.