Inhibition of ornithine decarboxylase induces embryonal carcinoma cell differentiation

Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line

Michael W. McBurney, Elizabeth Jones-Villeneuve, Mary K. Edwards et al. · Nature · 1982 · 674 citations

Developmental Biology, Tumor Innervation, Cell Specialization +9

Anti-proliferative properties of DL-α-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase

Pierre S. Mamont, Marie-Christine Duchesne, Jeffrey Grove et al. · Biochemical and Biophysical Research Communications · 1978 · 399 citations

Cultured Cells, Medicine, Dl-α-difluoromethyl Ornithine +5

Induction of the polyamine-biosynthetic enzymes in mouse epidermis and their specificity for tumor promotion.

Thomas G. O’Brien, R. C. Simsiman, R. K. Boutwell · PubMed · 1975 · 236 citations

Molecular Pharmacology, Skin Development, Polyamine-biosynthetic Enzymes +9

Stimulation of differentiation of several murine embryonal carcinoma cell lines by retinoic acid

Anton M. Jetten, M.E.R. Jetten, Michael I. Sherman · Experimental Cell Research · 1979 · 165 citations

Developmental Biology, Oncogenic Agent, Photocarcinogenesis +6

More Sensitive Automated Detection of Polyamines in Physiological Fluids and Tissue Extracts with o-Phthalaldehyde

Laurence J. Marton, Patrick L. Y. Lee · Clinical Chemistry · 1975 · 127 citations · Full text

Pharmaceutical Science, Engineering, Intensely Blue-fluorescing Product +18