Direct Nitration of Anilines Using Nitrocyclohexadienones

Abstract

Nitrocyclohexadienones (in particular, 2,3,5,6-tetrabromo-4-methyl-4-nitro-2,5-cyclohexadienone) are used as reagents for the direct nitration of anilines. Depending on the conditions, good yields of C-nitroanilines are obtained. Under the same conditions, N,N-dimethylaniline is converted into N-methyl-N-nitroaniline.