Penostatins F–I, novel cytotoxic metabolites from a Penicillium species separated from an Enteromorpha marine alga

Abstract

Penostatins F–I have been isolated from a strain of Penicillium sp. originally separated from the marine alga Enteromorpha intestinalis, and their stereostructures have been established on the basis of spectral analyses. All the compounds exhibit significant cytotoxicity against cultured P388 cells.