Medicinal Chemistry · 2005 · 50 citations · 0 references
Life SciencesBioinformaticsInfectious DiseasesMolecular VirologySequence AnalysisVirologyGenome VisualizationGenomic Data VisualizationViral DiagnosticsViral Genome OrganizationViral GenomicsViral InfectionsCoronavirus DiagnosticsNovel Virus IdentificationTwo-dimensional Cellular AutomataViral Genome DetectionViral Genome Sequencing
It has been observed by conducting an extensive analysis of the two-dimensional cellular automata images of known SARS-CoV genome sequences that the V-shaped cross-lines only exist in some special locations, and hence can be used as a fingerprint to identify the SARS sequences. Such a discovery can be used to rapidly and reliably diagnose SARS coronavirus for both basic research in laboratories and practical application in clinics. Keywords: cellular automata images, sars, rna genomic, visualization analysis, v-shaped cross-line pattern, parallel slash-line pattern