Evidence of an insulin generated pyruvate dehydrogenase stimulating factor in rat brain plasma membranes

Methods of Enzymology.

Henry Tauber · Journal of the American Chemical Society · 1956 · 1.7K citations

Life Sciences, Biochemistry, Enzyme Engineering +6

Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine.

Masato Kasuga, Yehiel Zick, D L Blith et al. · Journal of Biological Chemistry · 1982 · 439 citations · Full text

Life Sciences, Biochemistry, Endocrinology +16

Characterization of insulin-mediated phosphorylation of the insulin receptor in a cell-free system.

Yehiel Zick, Masato Kasuga, C. Ronald Kahn et al. · Journal of Biological Chemistry · 1983 · 224 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Evidence that insulin activates an intrinsic plasma membrane protease in generating a secondary chemical mediator.

Jonathan R. Seals, Michael Czech · Journal of Biological Chemistry · 1980 · 176 citations · Full text

Life Sciences, Biochemistry, Physiology +17

Activation of pyruvate dehydrogenase by direct addition of insulin to an isolated plasma membrane/mitochondria mixture: Evidence for generation of insulin's second messenger in a subcellular system

Jonathan R. Seals, Leonard Jarett · Proceedings of the National Academy of Sciences · 1980 · 174 citations · Full text

Life Sciences, Endocrinology, Physiology +12