Comparisons between mitochondrial genomes of domestic goat (<i>Capra hircus</i>) reveal the presence of numts and multiple sequencing errors

Abstract

As poor-quality sequences can produce misleading interpretations of both phylogeny and molecular evolution, we propose including a new link to each accession number in the nucleotide databases, named "external expertise", which could be openly and continually updated by non-anonymous searchers in order to validate good-quality data, or, conversely, to indicate possible problems in the sequence, such as DNA contamination or sequencing errors. This information could prove very useful over time to select good-quality sequences for in silico analyses.