A 3′UTR SNP in NLRP3 Gene is Associated With Susceptibility to HIV-1 Infection

Abstract

susceptibility to HIV-1 infection is associated with a 3'UTR NLRP3 polymorphism. This is the first report linking SNPs in the NALPs with HIV-1 infection, and further epidemiologic and functional studies are needed to deeper investigate the role of inflammasome in the susceptibility to HIV-1 infection.