Importance of the Efflux Pump Systems in the Resistance of <i>Mycobacterium tuberculosis</i> to Fluoroquinolones and Linezolid

Abstract

Therefore, these mechanisms are involved in the resistance to both compounds. It would be of interest to carry out further studies to determine to what extent these active efflux systems influence resistance to the different groups of drugs used in the treatment of tuberculosis, with a view to the possibility of using the inhibitors of these systems in future therapeutic applications.