New triterpene saponins from Ilex pubescens.

Abstract

Novel triterpenoid saponins, ilexsaponins B1, B2 and B3, have been isolated from the roots of Ilex pubescens. Degradative and spectroscopic studies have established their structures as shown in formulae 5, 6, and 7. Ilexsaponin B3 was found to possess an activity against experimental hypercholesteremia in mice.