Benzodiazepine-induced motor impairment linked to point mutation in cerebeilar GABAA receptor

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

Natural Sciences, Biophysics, Cell Biology +16

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

Kary B. Mullis, Fred Faloona · Methods in enzymology on CD-ROM/Methods in enzymology · 1987 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +11

High-efficiency transformation of mammalian cells by plasmid DNA.

C Chen, Hiroto Okayama · Molecular and Cellular Biology · 1987 · 5.3K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +13

[1] Production of single-stranded plasmid DNA

Jeffrey Vieira, Joachim Messing · Methods in enzymology on CD-ROM/Methods in enzymology · 1987 · 2.6K citations

Life Sciences, Biotechnology, Molecular Biology +12