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The Metabolism of Cobalt by the Normal Human Male
20
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References
1972
Year
Radioactive ContaminationRadiation ExposureTreatment VerificationOxidative StressRadiation TestingRadiation MedicineBody CompositionRadiopharmaceutical TherapyCarrier-free 58Cocl2Radiation OncologyHuman MetabolismNuclear MedicineMineral MetabolismRadiologyHealth SciencesBiochemistryRadiological SciencesMetabolomicsDosimetryWhole Body RetentionPhysiologyRadiation DoseRadioanalytical ChemistryNormal Human MaleMetabolismMedicineCarbonyl Metabolism
The whole body retention of cobalt after intravenous injection of carrier-free 58CoCl2 in saline solution has been measured in 16 men. The retention data for each subject have been analysed statistically and the best descriptions of the data are provided by equations with five exponential terms. Investigation levels for the radioisotopes of cobalt have been calculated for each subject. The average investigation level for 60CoCl2 computed from the data is an uptake of 1.2 μCi, which may be compared with the value of 24 μCi given in ICRP Publication 10. The coefficient of variation of the radiation dose to various members of the working population after a given uptake of radiocobalt was estimated to be 20%.