A Novel Closed-Circular Mitochondrial DNA with Properties of a Replicating Intermediate

Harumi Kasamatsu, Donald L. Robberson, Jerome Vinograd

Proceedings of the National Academy of Sciences · 1971 · 273 citations · 9 references

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Abstract

A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.

References

9