Are β‐Acylaminoacrylates Hydrogenated in the Same Way as α‐Acylaminoacrylates?

Abstract

Five catalyst–substrate complexes of the type [Rh(chiral ligand)(β-dehydroamino acid derivative)]BF4 were characterized for the first time by X-ray analysis (see example). Low-temperature NMR spectroscopy proved that three of these complexes are “major” substrate complexes, which lead to the main product in asymmetric hydrogenation, contrary to the known classical examples with analogous α-dehydroamino acid derivatives. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z461716_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.