Deficiencies in myeloid antigen‐presenting cells in women with cervical squamous intraepithelial lesions

Abstract

Low levels of peripheral blood MDCs and of MDDCs expressing CD86 and HLA-DR suggest that deficiencies in the ability of MDDC to present antigen to autologous T cells may lead to persistent infection with HPV and the development of cervical SILs in HPV-infected women.