Notoamides F−K, Prenylated Indole Alkaloids Isolated from a Marine-Derived <i>Aspergillus</i> sp.

Abstract

Six new prenylated indole alkaloids, named notoamides F-K (8-13), were isolated from a marine-derived Aspergillus sp. Their structures, including absolute configurations, were elucidated by spectroscopic methods. Notoamide I (11) showed weak cytotoxicity against HeLa cells with an IC(50) value of 21 microg/mL.