Notoamides F−K, Prenylated Indole Alkaloids Isolated from a Marine-Derived <i>Aspergillus</i> sp.

Sachiko Tsukamoto, Hikaru Kato, Masayuki Samizo, Yuka Nojiri, Hiroyuki Onuki, Hiroshi Hirota, Tomihisa Ohta

Journal of Natural Products · 2008 · 133 citations · 22 references

Concepts

Abstract

Six new prenylated indole alkaloids, named notoamides F-K (8-13), were isolated from a marine-derived Aspergillus sp. Their structures, including absolute configurations, were elucidated by spectroscopic methods. Notoamide I (11) showed weak cytotoxicity against HeLa cells with an IC(50) value of 21 microg/mL.

References

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