Distinct down-regulation of cardiac ?1- and ?2-adrenoceptors in different human heart diseases

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

George Scatchard · Annals of the New York Academy of Sciences · 1949 · 19.9K citations

Natural Sciences, Biophysics, Chemistry +9

Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure

Jay N. Cohn, T. Barry Levine, Maria Teresa Olivari et al. · New England Journal of Medicine · 1984 · 3.1K citations

Medicine, Cardiology, Clinical Cardiology +9

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

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Medicine, Cardiology, Physiology +14

Differentiation of Receptor Systems activated by Sympathomimetic Amines

A.M. Lands, A. Arnold, J.P. McAuliff et al. · Nature · 1967 · 2.1K citations

Medicine, Pharmacology, Neuropharmacology +13

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.

Michael R. Bristow, Robert Ginsburg, Victor A. Umans et al. · Circulation Research · 1986 · 1.3K citations · Full text

Medicine, Cardiology, Physiology +17