Phylogeny of Nuclear-Encoded Plastid-Targeted GAPDH Gene Supports Separate Origins for the Peridinin- and the Fucoxanthin Derivative-Containing Plastids of Dinoflagellates

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

Naruya Saitou, M Nei · Molecular Biology and Evolution · 1987 · 60.5K citations · Full text

Life Sciences, Bioinformatics, Evolutionary Biology +17

A simple method for displaying the hydropathic character of a protein

Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology · 1982 · 23.1K citations

Life Sciences, Biochemistry, Molecular Biology +12

The rapid generation of mutation data matrices from protein sequences

David T. Jones, William R. Taylor, Janet M. Thornton · Computer applications in the biosciences · 1992 · 7.1K citations

Life Sciences, Bioinformatics, Computational Biology +10

TREE-PUZZLE: maximum likelihood phylogenetic analysis using quartets and parallel computing

Heiko A. Schmidt, Korbinian Strimmer, Martin Vingron et al. · Bioinformatics · 2002 · 2.6K citations · Full text

Life Sciences, Bioinformatics, Evolutionary Biology +16