Repression of integrin-linked kinase by antidiabetes drugs through cross-talk of PPARγ- and AMPKα-dependent signaling: Role of AP-2α and Sp1

The Anti-diabetic Drugs Rosiglitazone and Metformin Stimulate AMP-activated Protein Kinase through Distinct Signaling Pathways

Lee G.D. Fryer, Asha Parbhu Patel, David Carling · Journal of Biological Chemistry · 2002 · 1K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14

Analysis of the DNA-binding and activation properties of the human transcription factor AP-2.

Trevor Williams, Robert Tjian · Genes & Development · 1991 · 521 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Thiazolidinediones and the Risk of Lung, Prostate, and Colon Cancer in Patients With Diabetes

Rangaswamy Govindarajan, Luke D. Ratnasinghe, Debra L. Simmons et al. · Journal of Clinical Oncology · 2007 · 332 citations · Full text

Medicine, Oncology, Pharmacology +13

Metformin is a potent inhibitor of endometrial cancer cell proliferation—implications for a novel treatment strategy

Leigh A. Cantrell, Chunxiao Zhou, Alberto A. Mendivil et al. · Gynecologic Oncology · 2009 · 332 citations

Medicine, Oncology, Pharmacology +11

Antiapoptotic Role of PPARβ in Keratinocytes via Transcriptional Control of the Akt1 Signaling Pathway

Nicolas Di‐Poï, Nguan Soon Tan, Liliane Michalik et al. · Molecular Cell · 2002 · 325 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16