Characterization and classification of matrix effects in biological samples analyses

Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC−MS/MS

B.K. Matuszewski, M.L. Constanzer, C.M. Chavez-Eng · Analytical Chemistry · 2003 · 5.2K citations

Pharmacy, Pharmaceutical Analysis, Pharmacokinetics +17

The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds

Ryan P. Bonfiglio, Richard C. King, Timothy Olah et al. · Rapid Communications in Mass Spectrometry · 1999 · 922 citations

Pharmacy, Pharmaceutical Analysis, Pharmaceutics +10

Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids:  A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

B.K. Matuszewski, M.L. Constanzer, C.M. Chavez-Eng · Analytical Chemistry · 1998 · 879 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +17

Quantitative Bioanalytical Methods Validation and Implementation: Best Practices for Chromatographic and Ligand Binding Assays

C.T. Viswanathan, Surendra K. Bansal, Brian Booth et al. · Pharmaceutical Research · 2007 · 815 citations

Pharmacy, Biochemistry, Chemistry +16

Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography–tandem mass spectrometry

Cara Polson, Pratibha Sarkar, Bev Incledon et al. · Journal of Chromatography B · 2003 · 678 citations

Life Sciences, Biochemistry, Molecular Biology +16