Impaired glucose tolerance (IGT) is associated with reduced insulin-induced suppression of glucagon concentrations

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

R. A. DeFronzo, J. D. Tobin, R Andres · American Journal of Physiology-Endocrinology and Metabolism · 1979 · 7.5K citations

Medicine, Biochemistry, Endocrinology +17

Insulin Resistance and Insulin Secretory Dysfunction as Precursors of Non-Insulin-Dependent Diabetes Mellitus: Prospective Studies of Pima Indians

Stephen Lillioja, David M. Mott, Maximilian Spraul et al. · New England Journal of Medicine · 1993 · 1.5K citations · Full text

Medicine, Endocrinology, Diabetology +14

Diabetes Mellitus: Report of a WHO Study Group.

Annals of Internal Medicine · 1986 · 1K citations

Medicine, Endocrinology, Internal Medicine +13

Plasma Insulin Responses to Oral and Intravenous Glucose: Studies in Normal and Diabetic Subjects*

Michael Perley, David Kipnis · Journal of Clinical Investigation · 1967 · 918 citations · Full text

Life Sciences, Endocrinology, Physiology +15

Role of Reduced Suppression of Glucose Production and Diminished Early Insulin Release in Impaired Glucose Tolerance

Asimina Mitrakou, David E. Kelley, Marian Mokáň et al. · New England Journal of Medicine · 1992 · 594 citations · Full text

Medicine, Endocrinology, Physiology +17