Determining Population and Developmental Pharmacokinetics of Metronidazole Using Plasma and Dried Blood Spot Samples From Premature Infants

Michael Cohen‐Wolkowiez, Mario R. Sampson, Barry T. Bloom, Antonio Arrieta, James L. Wynn, Karen Martz, Barrie Harper, Gregory L. Kearns, Edmund V. Capparelli, David S. Siegel,

The Pediatric Infectious Disease Journal · 2013 · 51 citations · 15 references

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Abstract

Simulations suggested the majority of infants in the neonatal intensive care unit (>80%) would meet the surrogate efficacy target using postmenstrual age-based dosing.

References

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