Downregulation of the Vascular Renin-Angiotensin System by Aerobic Training – Focus on the Balance Between Vasoconstrictor and Vasodilator Axes –

Abstract

Vascular RAS is not equally expressed in vessels, having crucial importance in the renal artery. In the renal SHR artery, training downregulates the vasoconstrictor and preserves the vasodilator axis while in other tissues and plasma training reduces both RAS axes, thus maintaining the vasoconstriction/vasodilatation balance in a lower level.