Diversity of sequence haplotypes associated with β-thalassaemia mutations in Algeria: implications for their origin

Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)

Charles R. Newton, Alexander Graham, Lesley Heptinstall et al. · Nucleic Acids Research · 1989 · 2.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.

Ulf Gyllensten · Proceedings of the National Academy of Sciences · 1988 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

Stuart H. Orkin, Haig H. Kazazian, Stylianos E. Antonarakis et al. · Nature · 1982 · 934 citations

Life Sciences, Genetics, Molecular Genetics +11

Archaic African and Asian lineages in the genetic ancestry of modern humans.

Rosalind M. Harding, Stephanie M. Fullerton, Robert Griffiths et al. · PubMed · 1997 · 414 citations

Life Sciences, Evolutionary Biology, Genetics +17

Nonrandom association of polymorphic restriction sites in the β-globin gene cluster

Stylianos E. Antonarakis, Corinne D. Boehm, Patricia J. Giardina et al. · Proceedings of the National Academy of Sciences · 1982 · 403 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12