CD4⁺PD-1⁺T Cells Acting as Regulatory Cells during the Induction of Anterior Chamber-Associated Immune Deviation

Abstract

CD4+PD-1+ T cells from ACAID mice, as regulatory cells, are involved in the induction of antigen-specific suppression in association with enhanced expression of IL-10. CD4+PD-1+ T cells in the murine spleen may represent a substantial population of regulatory T cells possibly responsible for the induction of ACAID after intracameral injection of antigen.