SINEs and LINEs cluster in distinct DNA fragments of Giemsa band size

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

David C. Schwartz, Charles R. Cantor · Cell · 1984 · 2.8K citations

Life Sciences, Genetics, Molecular Biology +14

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

Robert K. Moyzis, Judy M. Buckingham, L. Scott Cram et al. · Proceedings of the National Academy of Sciences · 1988 · 2.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

Gilbert Chu, Douglas Vollrath, Ronald W. Davis · Science · 1986 · 1.5K citations

Life Sciences, Biochemistry, Molecular Biology +11

Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

D. Pinkel, J. E. Landegent, Colin C. Collins et al. · Proceedings of the National Academy of Sciences · 1988 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries

Peter Lichter, Thomas Cremer, Jonathan Borden et al. · Human Genetics · 1988 · 1.2K citations

Life Sciences, Genetics, Molecular Biology +13