Low serum folate but normal homocysteine levels in patients with atherosclerotic vascular disease and matched healthy controls

Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

Robert Clarke, Leslie Daly, Killian Robinson et al. · New England Journal of Medicine · 1991 · 2.2K citations · Full text

Life Sciences, Biochemistry, Cardiology +15

Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum

W.J.H. Vermaak, S. Bissbort · Journal of Chromatography B Biomedical Sciences and Applications · 1991 · 685 citations

Life Sciences, Biochemistry, Clinical Biochemistry +6

Prospective Study of Coronary Heart Disease Incidence in Relation to Fasting Total Homocysteine, Related Genetic Polymorphisms, and B Vitamins

Aaron R. Folsom, F. Javier Nieto, Paul G. McGovern et al. · Circulation · 1998 · 608 citations · Full text

Medicine, Cardiology, Genetics +16

Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase.

Seok Seon Kang, Jiemin Zhou, Paul Wong et al. · PubMed · 1988 · 598 citations

Life Sciences, Biochemistry, Genetics +14

Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.

Erik S.G. Stroes, J Kastelein, Francesco Cosentino et al. · Journal of Clinical Investigation · 1997 · 587 citations · Full text

Medicine, Cardiology, Pharmacology +13