Parkinson’s disease-associated mutations in α-synuclein and UCH-L1 inhibit the unconventional secretion of UCH-L1

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

Mihael H. Polymeropoulos, Christian Lavedan, Elisabeth Leroy et al. · Science · 1997 · 8.2K citations

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α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

Maria Grazia Spillantini, R. Anthony Crowther, Ross Jakes et al. · Proceedings of the National Academy of Sciences · 1998 · 3.2K citations

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The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementia

J.J. Zarranz, Juan Carlos Gómez‐Esteban, Elena Lezcano et al. · Annals of Neurology · 2003 · 2.7K citations

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Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

Evangelia Emmanouilidou, Katerina Melachroinou, Theodoros I. Roumeliotis et al. · Journal of Neuroscience · 2010 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

The Neuron-Specific Protein PGP 9.5 Is a Ubiquitin Carboxyl-Terminal Hydrolase

Keith D. Wilkinson, Keunmyoung Lee, Seema S. Deshpande et al. · Science · 1989 · 873 citations

Life Sciences, Biochemistry, Molecular Biology +10