Concepedia

Transition Metal-Catalyzed N-Alkylation of NH Groups of Azoles with Alcohols

Norio Tanaka, Masataka Hatanaka, Yoshihisa Watanabe

Chemistry Letters · 1992 · 45 citations · 12 references

DOI

Concepts

Abstract

Abstract Azoles containing acidic NH-group react with various alcohols in the presence of catalytic amount of ruthenium-, rhodium-, and iridium- trialkylphosphite complexes to give the corresponding N-alkylated azoles in good to excellent yields.

References

12

Transition metal-catalysed N-alkylation of amines by alcohols

Ronald Grigg, T. R. B. MITCHELL, Somyote Sutthivaiyakit et al. · Journal of the Chemical Society Chemical Communications · 1981 · 431 citations

, , +16

The ruthenium catalyzed N-alkylation and N-heterocyclization of aniline using alcohols and aldehydes

Yoshihisa Watanabe, Yasushi Tsuji, Yukihiro Ohsugi · Tetrahedron Letters · 1981 · 349 citations

, , +8

The preparation and reactions of hydridochlorotris(triphenylphosphine)ruthenium(II) including homogeneous catalytic hydrogenation of alk-1-enes

P. S. Hallman, Bruce R. McGarvey, G. Wilkinson · Journal of the Chemical Society A Inorganic Physical Theoretical · 1968 · 265 citations

, , +16

Dichlorotris(triphenylphosphine)ruthenium-catalyzed hydrogen transfer from alcohols to saturated and .alpha.,.beta.-unsaturated ketones

Yoel Sasson, Jochanan Blum · The Journal of Organic Chemistry · 1975 · 222 citations

, , +7

Ruthenium-catalyzed N-alkylation and N-benzylation of aminoarenes with alcohols

Yoshihisa Watanabe, Yasushi Tsuji, Hitoshi Ige et al. · The Journal of Organic Chemistry · 1984 · 219 citations

, , +6