Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells

The anti-tumor effect of Ganoderma Lucidum is mediated by cytokines released from activated macrophages and T lymphocytes

Shengyuan Wang, Ming‐Ling Hsu, Hui‐Chi Hsu et al. · International Journal of Cancer · 1997 · 448 citations

Life Sciences, Cancer Biology, Immunology +17

Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell cycle arrest

Shwu‐Bin Lin, Chyi-Hann Li, Shiuh‐Sheng Lee et al. · Life Sciences · 2003 · 244 citations

Life Sciences, Biochemistry, Oncology +13

<i>Ganoderma lucidum</i> extract induces cell cycle arrest and apoptosis in MCF‐7 human breast cancer cell

Hongbo Hu, Nam‐Shik Ahn, Xinlin Yang et al. · International Journal of Cancer · 2002 · 233 citations

Medicine, Oncology, Pharmacology +14

Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides

Hung-Sen Chen, Yow‐Fu Tsai, Steven Lin et al. · Bioorganic & Medicinal Chemistry · 2004 · 164 citations

Life Sciences, Immunology, Oncology +14

Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: mechanism of action and isolation of an active substance.

Yoshiyuki Kimura, Masahiko Taniguchi, Kimiye Baba · PubMed · 2003 · 154 citations

Medicine, Oncology, Pharmacology +11