Supported Gold(III) Catalysts for Highly Efficient Three‐Component Coupling Reactions

Xin Zhang, Avelino Corma

Angewandte Chemie International Edition · 2008 · 263 citations · 62 references

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Abstract

Charged gold species stabilized on nanocrystalline CeO2 or ZrO2 are highly active catalysts for the one-pot, three-component coupling of aldehydes, amines, and alkynes/N-protected ethynylaniline, which yields multifunctionalized propargylamines and indoles in good to excellent yields (see picture; Ts=toluene-4-sulfonyl).

References

62