Improvement of lesions shown on MRI and CT scan by administration of dichloroacetate in patients with Leigh syndrome

SUBACUTE NECROTIZING ENCEPHALOMYELOPATHY IN AN INFANT

Denis Leigh · Journal of Neurology Neurosurgery & Psychiatry · 1951 · 788 citations · Full text

Medicine, Neurology, Pediatrics +8

Cytochrome <i>c</i> oxidase deficiency in leigh syndrome

Salvatore DiMauro, Serenella Servidei, Massimo Zeviani et al. · Annals of Neurology · 1987 · 363 citations

Life Sciences, Biochemistry, Pathology +14

Treatment of Lactic Acidosis with Dichloroacetate

Peter W. Stacpoole, Eloise Harman, Stephen H. Curry et al. · New England Journal of Medicine · 1983 · 256 citations

Medicine, Pharmacology, Pharmacotherapy +15

Cytochrome c oxidase-associated Leigh syndrome: Phenotypic features and pathogenetic speculations

Rudy Van Coster, Anne Lombes, Darryl C. De Vivo et al. · Journal of the Neurological Sciences · 1991 · 105 citations

Life Sciences, Genetics, Molecular Biology +6

Metabolic effects and pharmacokinetics of intravenously administered dichloroacetate in humans

Peter G. Wells, G. W. K. Moore, Daniel U. Rabin et al. · Diabetologia · 1980 · 94 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +7