Hyperthermia induced by open-field stress is blocked by salicylate

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

John R. Vane · Nature New Biology · 1971 · 8.6K citations

Life Sciences, Medicinal Chemistry, Pharmacology +10

Indomethacin and Aspirin abolish Prostaglandin Release from the Spleen

S. H. Ferreira, Salvador Moncada, John R. Vane · Nature New Biology · 1971 · 934 citations

Veterinary Medicine, Pharmacology, Inflammation +5

Effects on body temperature of prostaglandins of the A, E and F series on injection into the third ventricle of unanaesthetized cats and rabbits

A. S. Milton, S Wendlandt · The Journal of Physiology · 1971 · 357 citations

Medicine, Pharmacology, Physiology +11

Increased Plasma Interleukin-1 Activity in Women After Ovulation

Joseph G. Cannon, Charles A. Dinarello · Science · 1985 · 342 citations

Life Sciences, Gynecology, Immunology +13

Synthesis of interleukin 1/endogenous pyrogen in the brain of endotoxin-treated mice: a step in fever induction?

A. Fontana, Elisabetta Weber, J M Dayer · The Journal of Immunology · 1984 · 279 citations

Life Sciences, Immunology, Neuroscience +11