Novel Germline Mutation: EGFR V843I in Patient With Multiple Lung Adenocarcinomas and Family Members With Lung Cancer

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR

Daphne W. Bell, Ira Gore, Ross A. Okimoto et al. · Nature Genetics · 2005 · 532 citations

Medicine, Genetics, Oncology +14

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

Hongbin Ji, Danan Li, Liang Chen et al. · Cancer Cell · 2006 · 451 citations · Full text

Medicine, Genetics, Oncology +15

<i>EGFR</i> Tyrosine Kinase Domain Mutations Are Detected in Histologically Normal Respiratory Epithelium in Lung Cancer Patients

Ximing Tang, Hisayuki Shigematsu, B. Nebiyou Bekele et al. · Cancer Research · 2005 · 272 citations

Veterinary Medicine, Genetics, Oncology +16

Epidermal growth factor receptor mutations in needle biopsy/aspiration samples predict response to gefitinib therapy and survival of patients with advanced nonsmall cell lung cancer

Jin‐Yuan Shih, Chien‐Hung Gow, Chong‐Jen Yu et al. · International Journal of Cancer · 2005 · 172 citations

Medicine, Oncology, Pathology +17

Somatic Mutations of Epidermal Growth Factor Receptor in Bile Duct and Gallbladder Carcinoma

Francesco Leone, Giuliana Cavalloni, Ymera Pignochino et al. · Clinical Cancer Research · 2006 · 170 citations

Medicine, Molecular Biology, Oncology +17