Diagnostic Utility of Thyroid Transcription Factor–1 Expression in Adenocarcinomas Presenting in Serous Fluids

Abstract

Immunostaining with TTF-1 is a useful marker that can be applied to cytologic specimens. Anti-TTF-1 can be used as a reliable component of an antibody panel to support the diagnosis of adenocarcinoma of pulmonary origin in patients presenting with metastatic adenocarcinoma in serous fluid with an unknown primary site.