Concepedia

Tear and serum antibody levels in ocular herpetic infection: diagnostic precision of secretory IgA.

P D Fox, Peng T. Khaw, B.W. McBride, J I McGill, Kenneth Ward

British Journal of Ophthalmology · 1986 · 34 citations · 9 references

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Abstract

A sensitive enzyme linked immunosorbent assay (ELISA) was developed to evaluate the potential of herpes simplex virus (HSV) specific antibodies in the diagnosis of herpetic eye infection. The presence of HSV specific secretory IgA (sIgA) in tears was found to be diagnostic of infection. However, serum and tear HSV specific IgG and IgA were not considered reliable indicators of active infection.

References

9

3,3′,5,5′-Tetramethylbenzidine as an Ames Test Negative Chromogen for Horse-Radish Peroxidase in Enzyme-Immunoassay

E. S. Bos, Antoon A. van der Doelen, N. van Rooy et al. · Journal of Immunoassay · 1981 · 406 citations

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The management of ocular herpes.

PubMed · 1959 · 130 citations

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Immunoglobulins in Tears

Barbara H. McClellan, Charles R. Whitney, Lawrence P. Newman et al. · American Journal of Ophthalmology · 1973 · 125 citations

Immunohistologic Studies of Human Lacrimal Gland: Localization of Immunoglobulins, Secretory Component and Lactoferrin

Rudolph M. Franklin, Kenneth R. Kenyon, Thomas B. Tomasi · The Journal of Immunology · 1973 · 111 citations

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Occurrence of herpes- and adenovirus antibodies in patients with carcinoma of the cervix uteri.Measurement of antibodies to herpesvirus hominis (types 1 and 2), cytomegalovirus, EB-virus, and adenovirus

Bent Faber Vestergaard, A Hornsleth, Søren Nødskov Pedersen · Cancer · 1972 · 65 citations

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