A novel one pot synthesis of nitrogen containing heterocycles: an alternate methodology to the Biginelli and Hantzsch reactions

Abstract

Modified Biginelli and Hantzsch reactions were carried using environmentally benign processes. Neat reactants subjected to microwave radiation gave the required products more quickly and in better yields in comparison to traditional methodologies. The observed yields and enhancement in reaction rates are due to the solvent free conditions coupled with the use of microwave radiation.