Respiratory-chain enzyme activities in isolated mitochondria of lymphocytes from patients with<i>Parkinson′s disease</i>: Preliminary study

Abstract

The use of lymphocytes for investigating the respiratory chain enzymes provides an easy, noninvasive method to assess mitochondrial function in patients with PD. Furthermore, our study supports the hypothesis that a biochemical defect in the respiratory chain may be involved in the pathogenesis of PD.