Pathology of the Cardiac Conduction System in Systemic Lupus Erythematosus

Abstract

Article1 September 1965Pathology of the Cardiac Conduction System in Systemic Lupus ErythematosusTHOMAS N. JAMES, M.D., F.A.C.P., CLARENCE E. RUPE, M.D., F.A.C.P., RAYMOND W. MONTO, M.D., F.A.C.P.THOMAS N. JAMES, M.D., F.A.C.P., CLARENCE E. RUPE, M.D., F.A.C.P., RAYMOND W. MONTO, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-3-402 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCardiac involvement by systemic lupus erythematosus (SLE) is sometimes manifested by arrhythmias or conduction disturbances. How often the heart is found to be involved depends on how carefully such involvement is sought, but it has recently been suggested that cardiac lesions will develop at some time in nearly all patients with this disease, when life is prolonged by modern antibiotic and steroid therapy (1). Although the documented incidence of arrhythmias or conduction disturbances in SLE is seldom reported to be more than 10% (1-5), one can reasonably suspect that the undocumented paroxysmal disturbances in cardiac electrical mechanisms are considerably more...References1. BRIGDENBYWATERSLESSOFROSS WEGMHIP: The heart in systemic lupus erythematosus. Brit. Heart J. 22: 1, 1960. CrossrefMedlineGoogle Scholar2. HARVEYSHULMANTUMULTYCONLEYSHOENRICH AMLPCEH: Systemic lupus erythematosus: review of literature and clinical analysis of 138 cases. Medicine 33: 291, 1954. CrossrefMedlineGoogle Scholar3. DUBOISTUFFANELLI ELDL: Clinical manifestations of systemic lupus erythematosus. JAMA 190: 112, 1964. CrossrefMedlineGoogle Scholar4. KONGKELLUMHASERICK TQREJR: Clinical diagnosis of cardiac involvement in systemic lupus erythematosus. A correlation of clinical and autopsy findings in thirty patients. Circulation 26: 7, 1962. CrossrefMedlineGoogle Scholar5. 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JAMESNADEAU TNRA: The effects of vagal stimulation, eserine and atropine on retrograde pressure in the sinus node artery. Henry Ford Hosp. Med. Bull. 12: 23, 1964. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: THOMAS N. JAMES, M.D., F.A.C.P.; CLARENCE E. RUPE, M.D., F.A.C.P.; RAYMOND W. MONTO, M.D., F.A.C.P.Affiliations: Detroit, MichiganFrom the Department of Medicine, Henry Ford Hospital, Detroit, Mich.Supported in part by a grant from the Michigan Heart Association, Detroit, Mich., and grants H-5197 and H-7108, U. S. Public Health Service, Bethesda, Md.Requests for reprints should be addressed to Thomas N. James, M.D., Henry Ford Hospital, Detroit, Mich. 48202. 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XXVIII. Apoplexy of the heart.Intrathoracic lymphoma associated with atrial arrhythmias and atrioventricular conduction defectsThe sinus nodeAssociation of Maternal Systemic Lupus Erythematosus with Congenital Complete Heart BlockCardiac Toxicity of ClonidinePericardial effusion and mitral valve involvement in systemic lupus erythematosus. Echocardiographic study.Clinicopathologic correlations. De subitaneis mortibus. XXV. Sarcoid heart disease.Congenital heart block in newborns of mothers with connective tissue disease.De subitaneis mortibus. XXIII. Rheumatoid arthritis and ankylosing spondylitis.Conduction system in systemic lupus erythematosus with atrioventricular blockThe heart in systemic lupus erythematosus and the changes induced in it by corticosteroid therapyEntzündliche Herzerkrankungen und KardiomyopathienDe Subitaneis MortibusBrady-tachy syndromePersistent atrial standstillThe vasculature of the atrioventricular conduction system in heart blockBrief Reviews : The Sinus Node as a ServomechanismMysterious Sudden DeathTransient and Persistent Atrial Standstill with His Bundle LesionsCardiac conduction system: Fetal and postnatal developmentSudden death in babies: New observations in the heartMedical and physiological considerations in the use of artificial cardiac pacing. Part IThe coronary circulation and conduction system in acute myocardial infarctionAppearance of Hodgkin's disease in a patient with systemic lupus erythematosusPathology of small coronary arteriesRepetitive tachycardiaPathology of the Cardiac Conduction System in Thrombotic Thrombocytopenic PurpuraTHOMAS N. JAMES, M.D., F.A.C.P., RAYMOND W. MONTO, M.D., F.A.C.P. 1 September 1965Volume 63, Issue 3Page: 402-410KeywordsArrhythmiaFibrosisHeartHeart diseasesHospital medicineInflammationLesionsLupus erythematosusMedical servicesSteroid therapy ePublished: 1 December 2008 Issue Published: 1 September 1965 PDF downloadLoading ...