Concepedia

Osthol and curcumin as inhibitors of human Pgp and multidrug efflux pumps of Staphylococcus aureus: reversing the resistance against frontline antibacterial drugs

Prashant Joshi, Samsher Singh, Abubakar Wani, Sadhana Sharma, Shreyans K. Jain, Baljinder Singh, B.D. Gupta, Naresh K. Satti, Surrinder Koul, Inshad Ali Khan,

MedChemComm · 2014 · 62 citations · 58 references

DOI

Concepts

Abstract

Curcumin and osthol are identified as NorA pump inhibitors.

References

58

Cancer: Principles and Practice of Oncology.

Annals of Internal Medicine · 1991 · 8.5K citations

, , +10

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

R. L. Juliano, Victor Ling · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3.3K citations

, , +11

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

Stephen G. Aller, Jodie Yu, Andrew B. Ward et al. · Science · 2009 · 1.9K citations · Full text

, , +12

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

Chang-jie Chen, Janice E. Chin, Kazumitsu Ueda et al. · Cell · 1986 · 1.9K citations

, , +14

Cancer: Principles and Practice of Oncology.

Annals of Internal Medicine · 1986 · 1.1K citations

, , +10