Degradation of synthetic polymeric scaffolds for bone and cartilage tissue repairs

Abstract

Degradation studies are reported with emphasis on polymeric scaffolds in which degradation occurs viaester bond cleavage. The temporal and structural consequences of polymer degradation on TE scaffolds in the absence and in the presence of biological components in vitro and in vivo are described and compared. Finally, the functional improvement of degradable polymeric scaffolds for TEvia the formation of hybrid structures is presented.