Nuclear Magnetic Resonance of Rotational Mobility of Mouse Hemoglobin Labeled with [2- ¹³ C]Histidine

Abstract

Carbon-13 nuclear magnetic resonance studies were made on mouse hemoglobin specifically labeled at the C-2 histidine position. Measurement of the spin lattice relaxation times of the label before and after hemolysis of the erythrocytes provides information on the intracellular fluid viscosities.