Proceedings of the National Academy of Sciences · 1967 · 156 citations · 0 references
MedicineEndocrinologyPharmacologyBioenergeticsPathophysiologySignal TransductionDiabetes ManagementDiabetes MellitusInsulin ResistanceInsulin Signaling In MetabolismMuscle PathologyMuscle PhysiologyDiabetes Mellitus PathophysiologyInsulin Resistance SyndromeInsulin Resistance TreatmentMuscle Insulin SignalingSkeletal Muscle Glucose MetabolismSkeletal Muscle Glucose UptakeSkeletal Muscle Insulin Resistance
Currently, no pharmacological therapies treat skeletal muscle insulin resistance in pathological conditions such as type 2 diabetes, age-associated diseases, and cancer. Therefore, there is an unmet need to identify the molecular mechanisms ...The molecular events governing skeletal muscle glucose uptake have pharmacological potential for managing insulin resistance in conditions such as obesity, diabetes, and cancer. With no current pharmacological treatments to target skeletal muscle insulin ...