The Diagnostic Accuracy of Plasma BNP and NTproBNP in Patients Referred From Primary Care with sUspected Heart Failure: Results of the UK Natriuretic Peptide Study

Abstract

We have confirmed the value of the measurement of plasma BNP or NTproBNP as a 'rule-out' test for heart failure in patients currently referred by GPs to rapid access diagnostic clinics. A simple classification of the 12-lead ECG into 'normal' or 'abnormal' adds little value to ruling out heart failure in these circumstances. Further work is necessary to establish the best decision cut-points for use in clinical practice.