Clinical Course of Anti-Neutrophil Cytoplasmic Autoantibody-associated Glomerulonephritis and Systemic Vasculitis

Abstract

Patients with ANCA have various forms of necrotizing vascular inflammation, ranging from renal-limited disease to widespread systemic vasculitis, including polyarteritis nodosa and Wegener granulomatosis. Oral corticosteroids with either oral or intravenous cyclophosphamide appear to be equally effective therapy for ANCA-associated glomerulonephritis.